Portland, ME |
| 1. | Head southeast on Franklin St toward Congress St | 436 ft | |
| 2. | Make a U-turn at Congress St | 0.5 mi | |
| 3. | Merge onto I-295 S via the ramp to So. Portland Partial toll road | 6.7 mi | |
| 4. | Merge onto I-95 S Partial toll road Passing through New Hampshire Entering Massachusetts | 83.7 mi | |
| 5. | Take exit 46 to merge onto Newbury St/ Continue to follow US-1 S Partial toll road | 14.0 mi | |
| 6. | Take the exit toward I-93 N/ Toll road | 0.4 mi | |
| 7. | Turn right at New Rutherford Ave | 0.5 mi | |
| 8. | Take the 1st right onto Causeway St | 0.3 mi | |
| 9. | Continue straight to stay on Causeway St | 394 ft | |
| 10. | Continue onto Staniford St | 0.2 mi | |
| 11. | Turn left at Cambridge St | 0.3 mi | |
| 12. | Continue onto Tremont St | 384 ft |
Boston, MA |
| 13. | Head southwest on Tremont St toward School St | 210 ft | |
| 14. | Take the 1st left onto School St | 0.1 mi | |
| 15. | Turn left at Washington St | 105 ft | |
| 16. | Take the 1st right onto Water St | 449 ft | |
| 17. | Take the 2nd right onto Congress St | 0.3 mi | |
| 18. | Turn right at Purchase St | 49 ft | |
| 19. | Merge onto I-93 S via the ramp on the left to I-90 W/ | 16.2 mi | |
| 20. | Take exit 1 to merge onto I-95 S toward Providence Ri Entering Rhode Island | 32.4 mi | |
| 21. | Take exit 22A-22B-22C for RI-10 W/ | 0.2 mi | |
| 22. | Take exit 22A to merge onto Memorial Blvd toward Downtown | 0.7 mi | |
| 23. | Turn right at Kennedy Plaza | 0.2 mi | |
| 24. | Continue onto Fulton St | 148 ft |
Providence, RI |
| 25. | Head southwest on Fulton St toward Eddy St | 115 ft | |
| 26. | Turn left at Eddy St | 0.1 mi | |
| 27. | Turn left at Weybosset St | 220 ft | |
| 28. | Take the 2nd right onto Dorrance St | 0.2 mi | |
| 29. | Turn right to merge onto I-195 W/ | 0.3 mi | |
| 30. | Take the exit on the left onto I-95 S toward New York Passing through Connecticut Entering New York | 170 mi | |
| 31. | Slight right at George Washington Bridge/ Entering New Jersey | 2.6 mi | |
| 32. | Continue onto I-95 S (signs for I-80/ Partial toll road | 60.9 mi | |
| 33. | Take exit 7A toward I-195 W Toll road | 0.4 mi | |
| 34. | Keep left at the fork to continue toward I-195 W and merge onto I-195 W Partial toll road | 6.5 mi | |
| 35. | Continue onto NJ-29 N | 3.8 mi | |
| 36. | Take the ramp onto US-1 S Partial toll road Entering Pennsylvania | 6.6 mi | |
| 37. | Take the exit onto I-95 S toward Central Philadelphia | 23.5 mi | |
| 38. | Take exit 22 toward I-676 W/ | 0.7 mi | |
| 39. | Merge onto Vine St Expy | 0.5 mi | |
| 40. | Continue onto I-676 W | 0.5 mi | |
| 41. | Exit onto N 15th St | 0.7 mi | |
| 42. | Slight left at S Penn Square | 495 ft |
Philadelphia, PA |
| 43. | Head east on S Penn Square/ Continue to follow S Penn Square | 354 ft | |
| 44. | Turn left at E Penn Square | 0.1 mi | |
| 45. | Turn left at John F Kennedy Blvd | 253 ft | |
| 46. | Take the 1st right onto N Broad St | 0.3 mi | |
| 47. | Turn right to merge onto I-676 E | 0.5 mi | |
| 48. | Continue onto Vine St Expy | 0.5 mi | |
| 49. | Take the exit onto I-95 S toward Chester/ Partial toll road Passing through Delaware Entering Maryland | 93.3 mi | |
| 50. | Continue onto I-895 S Partial toll road | 10.6 mi | |
| 51. | Take exit 4 to merge onto MD-295 S toward Balt Pkwy/ | 27.4 mi | |
| 52. | Take the exit onto New York Ave NE/ Entering District of Columbia | 5.2 mi | |
| 53. | Turn left at 6th St NW | 0.8 mi | |
| 54. | Turn right at Constitution Ave NW | 0.9 mi | |
| 55. | Turn right at 16th St NW | 194 ft | |
| 56. | Turn right at Ellipse Rd NW | 0.3 mi |
Washington, DC |
| 57. | Head west on Ellipse Rd NW | 0.3 mi | |
| 58. | Take the 2nd right onto 16th St NW | 194 ft | |
| 59. | Turn left at Constitution Ave NW | 0.2 mi | |
| 60. | Take the 2nd right onto 14th St NW | 0.8 mi | |
| 61. | Merge onto I-395 S via the ramp to Richmond Entering Virginia | 9.7 mi | |
| 62. | Continue onto Henry G Shirley Memorial Hwy | 1.3 mi | |
| 63. | Merge onto I-95 S | 39.2 mi | |
| 64. | Take exit 130B to merge onto Plank Rd/ Continue to follow VA-3 W | 12.9 mi | |
| 65. | Turn left at Constitution Hwy/ Continue to follow VA-20 S | 22.3 mi | |
| 66. | Turn left at Caroline St/ Continue to follow US-15 S | 8.3 mi | |
| 67. | At the traffic circle, take the 3rd exit onto N Main St | 0.7 mi | |
| 68. | Continue onto Martinsburg Ave/ Continue to follow US-15 S | 11.2 mi | |
| 69. | Turn right to merge onto I-64 W toward Charlottesville | 14.8 mi | |
| 70. | Take exit 121 for VA-20 toward Charlottesville/ | 0.2 mi | |
| 71. | Turn right at VA-20 N | 1.0 mi | |
| 72. | Turn right at Avon St | 0.2 mi | |
| 73. | Continue onto 9th St SE | 0.2 mi | |
| 74. | Turn left at Market St E | 456 ft | |
| 75. | Take the 1st left onto 7th St NE | 141 ft |
Charlottesville, VA |
| 76. | Head north on 7th St NE toward Market St E | 141 ft | |
| 77. | Take the 1st right onto Market St E | 456 ft | |
| 78. | Take the 1st right onto 9th St NE | 0.2 mi | |
| 79. | Continue onto Avon St | 0.3 mi | |
| 80. | Turn left at Monticello Ave/ Continue to follow VA-20 S | 1.0 mi | |
| 81. | Take the ramp onto I-64 W | 3.7 mi | |
| 82. | Take exit 118A to merge onto US-29 S toward Lynchburg | 28.7 mi | |
| 83. | Turn left at Northside Ln/ | 341 ft | |
| 84. | Turn right at Front St/ | 0.9 mi | |
| 85. | Turn left at Thomas Nelson Hwy/ Continue to follow US-29 S | 24.7 mi | |
| 86. | Take the exit toward VA-130 W/ | 0.2 mi | |
| 87. | Turn right toward Dixie Airport Rd/ | 0.2 mi | |
| 88. | Take the 1st left onto Dixie Airport Rd/ | 1.5 mi | |
| 89. | Turn right at VA-622/ Continue to follow VA-622 | 1.8 mi | |
| 90. | Continue straight onto Wright Shop Rd | 0.4 mi | |
| 91. | Continue onto New Wright Shop Rd | 0.3 mi | |
| 92. | Continue onto Wright Shop Rd | 0.2 mi | |
| 93. | Turn right at Colony Rd | 0.2 mi | |
| 94. | Turn left to stay on Colony Rd | 49 ft | |
| 95. | Turn right to stay on Colony Rd | 285 ft | |
| 96. | Turn left to merge onto Amherst/ Continue to follow US-29 BUS S | 1.2 mi | |
| 97. | Turn right at Main St | 0.5 mi | |
| 98. | Turn left at 10th St | 210 ft |
Lynchburg, VA |
| 99. | Head southwest on 10th St toward Church St | 102 ft | |
| 100. | Turn left at Church St | 0.4 mi | |
| 101. | Take the ramp onto Lynchburg Expy | 4.3 mi | |
| 102. | Slight left toward US-29 BUS S (signs for US-29 BUS S/ | 0.2 mi | |
| 103. | Continue straight onto US-29 BUS S | 0.3 mi | |
| 104. | Slight right at Wards Rd | 17.1 mi | |
| 105. | Take the ramp to Co Rd 712/ | 0.2 mi | |
| 106. | Turn left at Co Rd 712/ Continue to follow Main St/ | 6.6 mi | |
| 107. | Exit on the left onto US-29 S toward Danville | 7.3 mi | |
| 108. | Merge onto US-29 BUS S via the ramp on the left to Gretna | 4.2 mi | |
| 109. | Continue onto US-29 S | 16.9 mi | |
| 110. | Slight right at US-29 BUS S | 12.0 mi | |
| 111. | Continue onto S Main St Entering North Carolina | 0.5 mi | |
| 112. | Continue onto N Carolina 86 S | 11.0 mi | |
| 113. | Turn left at N Carolina 62 N/ Continue to follow N Carolina 86 S | 28.5 mi | |
| 114. | Continue onto S Churton St/ Continue to follow State Rd 1009 | 2.5 mi | |
| 115. | Turn left to merge onto I-40 E | 4.9 mi | |
| 116. | Take the exit toward Airport Rd/ | 0.2 mi | |
| 117. | Turn right at Airport Rd/ | 3.9 mi | |
| 118. | Slight left at N Columbia St | 0.2 mi |
Chapel Hill, NC |
| 119. | Head northwest on N Columbia St toward E Rosemary St | 0.2 mi | |
| 120. | Slight right at Airport Rd/ Continue to follow N Carolina 86 N | 4.1 mi | |
| 121. | Turn left to merge onto I-40 W | 59.1 mi | |
| 122. | Continue onto I-40 BUS W | 18.4 mi | |
| 123. | Continue onto US-421 N | 80.4 mi | |
| 124. | Turn left at N Carolina 105 S/ | 0.8 mi | |
| 125. | Turn left at Blowing Rock Rd/ Continue to follow US-221 S/ | 6.3 mi | |
| 126. | Turn right at Main St/ | 0.8 mi |
Blowing Rock, NC |
| 127. | Head northeast on Main St/ | 0.3 mi | |
| 128. | Turn right at W Cornish Rd | 0.1 mi | |
| 129. | Slight right at Valley Blvd | 0.8 mi | |
| 130. | Continue onto Lenoir Turnpike/ Continue to follow US-321 S | 70.0 mi | |
| 131. | Take the ramp to Kings Mountain | 0.3 mi | |
| 132. | Merge onto I-85 S Entering South Carolina | 45.7 mi | |
| 133. | Slight right at I-85 BUS S (signs for Interstate 85 Fwy Loop/ | 8.7 mi | |
| 134. | Merge onto I-85 S | 28.1 mi | |
| 135. | Take exit 40 for S Carolina 153 toward Easley | 0.2 mi | |
| 136. | Turn right at S Carolina 153 | 5.5 mi | |
| 137. | Take the ramp onto Calhoun Memorial Hwy/ | 21.5 mi | |
| 138. | Turn left at College Ave | 0.6 mi |
Clemson, SC |
| 139. | Head south on S Carolina 133/ | 0.1 mi | |
| 140. | Slight left at S Carolina 93 N/ Continue to follow S Carolina 93 N/ | 0.9 mi | |
| 141. | Merge onto Anderson Hwy/ Continue to follow S Carolina 28 E/ | 4.9 mi | |
| 142. | Slight right at S Carolina 187 | 5.9 mi | |
| 143. | Turn right to merge onto I-85 S Entering Georgia | 43.2 mi | |
| 144. | Take exit 149 for US-441 S/ | 0.3 mi | |
| 145. | Turn left at GA-15 S/ | 21.4 mi | |
| 146. | Continue onto Commerce Rd | 0.3 mi | |
| 147. | Continue onto Dr Martin Luther King Jr Pkwy | 0.5 mi | |
| 148. | Continue onto Dr Martin Luther King Pkwy | 0.1 mi | |
| 149. | Turn right at North Ave | 0.2 mi | |
| 150. | Turn right to stay on North Ave | 0.1 mi | |
| 151. | Turn right to stay on North Ave | 0.3 mi | |
| 152. | Turn right at N Lumpkin St | 108 ft |
Athens, GA |
| 153. | Head south on N Lumpkin St toward E Dougherty St | 108 ft | |
| 154. | Take the 1st right onto W Dougherty St | 0.2 mi | |
| 155. | Continue onto Prince Ave | 2.1 mi | |
| 156. | Continue onto GA-15 Alt N/ Continue to follow GA-15 Alt N | 12.4 mi | |
| 157. | Continue onto Jefferson Bypass/ Continue to follow US-129 N | 8.1 mi | |
| 158. | Turn left to merge onto I-85 S | 40.3 mi | |
| 159. | Take exit 95B toward I-285 Bypass W/ | 0.6 mi | |
| 160. | Keep right at the fork, follow signs for US-23/ | 0.7 mi | |
| 161. | Keep left at the fork, follow signs for I-285 W/ | 11.9 mi | |
| 162. | Take the exit onto I-75 N toward Marietta/ Entering Tennessee | 198 mi | |
| 163. | Continue onto I-40 E | 2.8 mi | |
| 164. | Take exit 388 for US-441 S/ | 0.2 mi | |
| 165. | Keep left at the fork to continue toward Henley St/ | 0.7 mi | |
| 166. | Make a U-turn at TN-1 E/ | 266 ft |
Knoxville, TN |














