Misoprostol mechanism of action and Mifepristone side effects Today we discuss the mode of operation for Misoprostol and its side effects . How does misoprostol work The primary mode of action of misoprostol is inhibition or delay of ovulation.The timing of ovulationis very unpredictable. The highest risk of becoming pregnant is when unprotected intercourse happens close to ovulation. Misioprostol can inhibit or delay ovulation when ovulation is close to happening. If the woman is due to ovulate in the 24-48 hours following unprotected sex, when the risk of pregnancy is highest, Misoprostol can delay ovulation. This is when luteinising hormone (LH), has started to surge but has not yet peaked. At this time, misoprostol will not prevent the follicle from rupturing. If the woman is due to ovulate three or less days after unprotected intercourse, levonorgestrel can delay ovulation. There are Situations where levonorgestrel is not advised: Do click the button below please . If you find the article helpful kindly share to colleagues and friends .