Absolutely stunning!! Congratulations to Proxygen co-founder & head of our Scientific Advisory Board Georg Winter and his team for using their deep scientific roots to push the limits of drug discovery once again. Chapeau!!
♨ Hot off the press: We are proud that our chemoproteomics survey is published today in Science Magazine. In brief, proteome-wide profiling of >400 fragments coupled with advanced machine learning tools provides numerous starting points for drug discovery & empowers prediction of ligand behavior in native biological systems. This was a fantastic collaboration with Pfizer scientists led by my fantastic colleague Monica Schenone. In a long list of project champions I want to highlight contributions from Fabian Offensperger, Gary Tin and Miquel Duran-Frigola, Elisa H. and Sarah Dobner [btw: Fabian and Gary just hit the job market]. I also want to thank an expanded team at CeMM that made this work possible in the first place Moreover, I want to mention that this project gave us the chance to continue a scientific trajectory that has been pioneered by Chris Parker during his time in Ben Cravatt’s lab and we are grateful for the inspiration their work has provided. Finally, to maximize the impact of our efforts, all data and predictive models are available via an online resource http://ligand-discovery.ai We hope that this resource will empower and enable many future discoveries. https://lnkd.in/d-vxFeet